An acetylcholinesterase inhibitor , eserine , induces long - term 1 depression at CA 3 - CA 1 synapses in the hippocampus of
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AUTHORS: 4 Robert Alan Mans 2, 4 5 1) conception and design of research 6 2) performed experiments 7 3) data analysis 8 4) interpretation of results 9 5) prepared figures 10 6) drafted manuscript 11 7) edited and revised figures or manuscript 12 8) approved final version of manuscript 13 Brian A. Warmus 14 1) performed experiments 15 2) analyzed data 16 3) interpreted results of experiments 17 Caroline C. Smith 18 1) performed experiments 19 2) analyzed data 20 3) interpreted results of experiments 21 Lori L. McMahon 22 1) conception and design of research 23 2) interpretation of results 24 3) edited and drafted manuscript 25 4) approved final version of manuscript 26 27 AFFILIATIONS: 28 Department of Cell, Developmental and Integrative Biology, University of Alabama at 29 Birmingham; Birmingham, AL 30 Department of Physiology and Biophysics, University of Alabama at Birmingham; 31 Birmingham, AL 32 Department of Neurobiology, University of Alabama at Birmingham, Birmingham AL 33 Department of Biology, Armstrong State University; Savannah, GA 34 35 *Authors contributed equally to this work 36 37 RUNNING HEAD: 38 Eserine induces LTD in the hippocampus. 39 ADDRESS FOR CORRESPONDENCE 40 Lori L. McMahon 41 MCLM 960 42 Birmingham, AL 35233 43 [email protected]; 205-934-3523 44 Articles in PresS. J Neurophysiol (August 20, 2014). doi:10.1152/jn.00048.2014
منابع مشابه
An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats.
Studies in humans and rodents support a role for muscarinic ACh receptor (mAChR) and nicotinic AChR in learning and memory, and both regulate hippocampal synaptic plasticity using complex and often times opposing mechanisms. Acetylcholinesterase (AChE) inhibitors are commonly prescribed to enhance cholinergic signaling in Alzheimer's disease in hopes of rescuing cognitive function, caused, in p...
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